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Listar por autor "Guerra Castellano, Alejandra"
Mostrando ítems 1-12 de 12
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Artículo
Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV
Pérez Mejías, Gonzalo; Guerra Castellano, Alejandra; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Elsevier, 2019)The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense ...
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Artículo
Exploring protein phosphorylation by combining computational approaches and biochemical methods
Pérez Mejías, Gonzalo; Velázquez Cruz, Alejandro; Guerra Castellano, Alejandra; Baños Jaime, Blanca; Díaz Quintana, Antonio Jesús; González Arzola, Katiuska; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Elsevier, 2020)Post-translational modifications of proteins expand their functional diversity, regulating the response of cells to a ...
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Artículo
Long distance electron transfer through the aqueous solution between redox partner proteins
Lagunas, Anna; Guerra Castellano, Alejandra; Nin Hill, Alba; Díaz Moreno, Irene; Rosa Acosta, Miguel Ángel de la; Samitier, Josep; Rovira, Carme; Gorostiza, Pau (Nature Research, 2018)Despite the importance of electron transfer between redox proteins in photosynthesis and respiration, the inter-protein ...
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Artículo
Mitochondrial cytochrome c shot towards histone chaperone condensates in the nucleus
González Arzola, Katiuska; Guerra Castellano, Alejandra; Rivero Rodríguez, Francisco; Casado Combreras, Miguel Ángel; Pérez Mejías, Gonzalo; Díaz Quintana, Antonio Jesús; Díaz Moreno, Irene; Rosa Acosta, Miguel Ángel de la (Wiley-Blackwell, 2021)Despite mitochondria being key for the control of cell homeostasis and fate, their role in DNA damage response is usually ...
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Artículo
Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria
Guerra Castellano, Alejandra; Díaz Quintana, Antonio Jesús; Pérez Mejías, Gonzalo; Elena-Real, Carlos A.; González Arzola, Katiuska; García Mauriño, Sofía M.; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (National Academy of Sciences, 2018)Respiratory cytochrome c has been found to be phosphorylated at tyrosine 97 in the postischemic brain upon neuroprotective ...
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Artículo
Phosphorylation disrupts long-distance electron transport in cytochrome c
Gomila, Alexandre M.J.; Pérez Mejías, Gonzalo; Nin-Hill, Alba; Guerra Castellano, Alejandra; Casas Ferrer, Laura; Ortiz Tescari, Sthefany; Díaz Quintana, Antonio Jesús; Samitier, Josep; Rovira, Carme; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene; Gorostiza, Pau; Giannotti, Marina I.; Lagunas, Anna (Springer Nature, 2022)t has been recently shown that electron transfer between mitochondrial cytochrome c and the cytochrome c1 subunit of the ...
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Tesis Doctoral
Phosphorylation of cytochrome C: functional and structural features
Guerra Castellano, Alejandra (2017-01-27)Post-translational modifications often modulate protein function. Actually, phosphorylation of cytochrome c occurs in vivo ...
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Artículo
Post-Translational Modifications of Cytochrome c in Cell Life and Disease
Guerra Castellano, Alejandra; Márquez Escudero, Inmaculada; Pérez Mejías, Gonzalo; Díaz Quintana, Antonio Jesús; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (MDPI, 2020)Mitochondria are the powerhouses of the cell, whilst their malfunction is related to several human pathologies, including ...
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Artículo
Respiratory complexes III and IV can each bind two molecules of cytochrome c at low ionic strength
Moreno Beltrán, José Blas; Díaz Moreno, Irene; González Arzola, Katiuska; Guerra Castellano, Alejandra; Velázquez Campoy, Adrián; Rosa Acosta, Miguel Ángel de la; Díaz Quintana, Antonio Jesús (Elsevier, 2015)The transient interactions of respiratory cytochrome c with complexes III and IV is herein investigated by using heterologous ...
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Artículo
Structural and functional insights into lysine acetylation of cytochrome c using mimetic point mutants
Márquez Escudero, Inmaculada; Pérez Mejías, Gonzalo; Guerra Castellano, Alejandra; Olloqui Sariego, José Luis; Andreu Fondacabe, Rafael Jesús; Calvente Pacheco, Juan José; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Wiley-Blackwell, 2021)Post-translational modifications frequently modulate protein functions. Lysine acetylation in particular plays a key role ...
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Artículo
Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48
Moreno Beltrán, José Blas; Guerra Castellano, Alejandra; Díaz Quintana, Antonio Jesús; Conte, Rebecca del; García Mauriño, Sofía M.; González Arzola, Katiuska; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (National Academy of Sciences, 2017)Regulation of mitochondrial activity allows cells to adapt to changing conditions and to control oxidative stress, and ...
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Artículo
Wheel and Deal in the Mitochondrial Inner Membranes: The Tale of Cytochrome c and Cardiolipin
Díaz Quintana, Antonio Jesús; Pérez Mejías, Gonzalo; Guerra Castellano, Alejandra; Rosa Acosta, Miguel Ángel de la; Díaz Moreno, Irene (Hindawi, 2020)Cardiolipin oxidation and degradation by different factors under severe cell stress serve as a trigger for genetically ...